Imprimir Ver referencias Citación Disclaimer: These citations have been automatically generated based on the information we have and it may not be 100% accurate. Please consult the latest official manual style if you have any questions regarding the format accuracy. AMA Citation Dougherty B, Chan A. Dougherty B, & Chan A Dougherty, Brian, and Alex Chan. Ultrasound effective for identifying in-transit metastases in patients with cutaneous melanoma. 2 Minute Medicine, 5 noviembre 2020. McGraw-Hill, 2020. AccessMedicina. https://accessmedicina.mhmedical.com/updatesContent.aspx?gbosid=554741§ionid=251645689APA Citation Dougherty B, Chan A. Dougherty B, & Chan A Dougherty, Brian, and Alex Chan. (2020). Ultrasound effective for identifying in-transit metastases in patients with cutaneous melanoma. (2020). 2 minute medicine. McGraw-Hill. https://accessmedicina.mhmedical.com/updatesContent.aspx?gbosid=554741§ionid=251645689.MLA Citation Dougherty B, Chan A. Dougherty B, & Chan A Dougherty, Brian, and Alex Chan. "Ultrasound effective for identifying in-transit metastases in patients with cutaneous melanoma." 2 Minute Medicine McGraw-Hill, 2020, https://accessmedicina.mhmedical.com/updatesContent.aspx?gbosid=554741§ionid=251645689. Descargar archivo de la citación: RIS (Zotero) EndNote BibTex Medlars ProCite RefWorks Reference Manager Mendeley © Copyright Clip Capítulo completo Sólo figuras Sólo cuadros Solo Videos Supplementary Content Ultrasound effective for identifying in-transit metastases in patients with cutaneous melanoma by Brian Dougherty, Alex Chan Listen +Originally published by 2 Minute Medicine® (view original article). Reused on AccessMedicine with permission. +1. Among patients with cutaneous melanoma, ultrasound evaluation identified in half of patients in-transit metastases that were otherwise not apparent during clinical examination and changed the course of management for a third of patients. +Evidence Leve Rating: 3 (Average) +In-transit metastases (ITMs), or lesions that develop in lymphatics between the primary tumor site and the regional lymph node field, occur in about 4% of patients with cutaneous melanoma. ITMs carry serious prognostic implications; approximately 43% of patients will go on to develop lethal, distant metastases. Thus, reliable ways of identifying ITMs are important for the management of patients with melanoma. This case series from an Australian institution evaluated the impact of using high-frequency ultrasound examination in patients with melanoma and ITMs, specifically looking at the incidence of additional ITMs, the false-positive rate, and the impact on management. 28 patients (median [IQR] age = 72 [63-77] years, 57% male) with a total of 40 ITMs were studied. Ultrasound examination identified additional ITMs in 54% of patients compared with clinical examination alone. Most of these additional ITMs were closer to the regional lymph node field than clinically apparent ITMs. The sensitivity and specificity of detecting additional metastases was 78% and 90%, respectively, with only one false-positive node confirmed after excision. Of note, a previous study found the sensitivity and specificity of PET/CT, a radiation-based imaging modality, for staging patients with ITMs to be 58% and 83%, respectively. Importantly, in 32% of patients, subsequent medical or surgical management was influenced by ultrasound evaluation. In all, this study suggests that ultrasound is a useful staging modality for patients with cutaneous melanoma as it both sensitive and specific for ITMs and has the potential to affect the course of management. +Click to read the study in Melanoma +©2020 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.