Imprimir Ver referencias Citación Disclaimer: These citations have been automatically generated based on the information we have and it may not be 100% accurate. Please consult the latest official manual style if you have any questions regarding the format accuracy. AMA Citation Wang Y, Bhangu A. Wang Y, & Bhangu A Wang, Yidi, and Avneesh Bhangu. Gluten intake in females without celiac disease is not associated with cognitive function. 2 Minute Medicine, 23 junio 2021. McGraw Hill, 2021. AccessMedicina. https://accessmedicina.mhmedical.com/updatesContent.aspx?gbosid=564089§ionid=256909281APA Citation Wang Y, Bhangu A. Wang Y, & Bhangu A Wang, Yidi, and Avneesh Bhangu. (2021). Gluten intake in females without celiac disease is not associated with cognitive function. (2021). 2 minute medicine. McGraw Hill. https://accessmedicina.mhmedical.com/updatesContent.aspx?gbosid=564089§ionid=256909281.MLA Citation Wang Y, Bhangu A. Wang Y, & Bhangu A Wang, Yidi, and Avneesh Bhangu. "Gluten intake in females without celiac disease is not associated with cognitive function." 2 Minute Medicine McGraw Hill, 2021, https://accessmedicina.mhmedical.com/updatesContent.aspx?gbosid=564089§ionid=256909281. Descargar archivo de la citación: RIS (Zotero) EndNote BibTex Medlars ProCite RefWorks Reference Manager Mendeley © Copyright Clip Capítulo completo Sólo figuras Sólo cuadros Solo Videos Supplementary Content Gluten intake in females without celiac disease is not associated with cognitive function by Yidi Wang, Avneesh Bhangu Listen +Originally published by 2 Minute Medicine® (view original article). Reused on AccessMedicine with permission. +1. In middle-aged women without celiac disease, there is no significant association between gluten intake and cognitive function across quintiles of gluten intake. +2. Further stratification by potential confounding factors such as age, smoking status, and history of diabetes also yielded null results. +Evidence Rating Level: 2 (Good) +In patients with celiac disease, gluten intake, which triggers severe autoimmune responses, has been linked with cognitive impairment. However, whether gluten intake is associated with cognitive impairment in individuals without celiac disease or nonceliac gluten sensitivity is unclear. +This prospective cohort study aimed to determine if long-term gluten intake in women without celiac disease is associated with cognitive function. Dietary data from 13,494 women were collected every 4 years from 1991-2015. The primary outcome was cognitive function, which was measured using Cogstate Brief Battery™, an online, self-administered assessment commonly used to measure cognitive decline in patients with Alzheimer’s Disease and other neuropsychiatric conditions. Cognitive scores in 1) psychomotor speed and attention, 2) learning and working memory, and 3) global cognition were collected from 2014-2019. Women who did not complete the full cognitive assessment, had implausible low scores suggestive of technical errors, previous history of stroke, or diagnosis of celiac anytime during study period were excluded. Overall, there were no significant associations between amount of gluten intake and cognition scores. Further stratification by potential confounders such as age, smoking status, BMI, depression status, and history of diabetes, hypertension, and hypercholesterolemia mostly yielded null results. Lastly, changes in gluten intake pattern during study period was also not associated with cognitive scores. Overall, this large-sized, long-term cohort study suggests that gluten intake is not associated with cognitive impairment in women without celiac disease. However, there is limit in generalizability of these results, and further studies with longitudinal assessment of cognitive function and in both female and male patients are warranted. +Click to read the study in JAMA Network Open +©2021 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.